Ocular allergy
Adult: As combination preparation containing naphazoline HCl 0.05% and antazoline phosphate 0.5% : Apply 1-2 drops in the affected eye 4 times daily.
Chỉ định và Liều dùng
Ophthalmic
Ocular allergy Adult: As combination preparation containing naphazoline HCl 0.05% and antazoline phosphate 0.5% : Apply 1-2 drops in the affected eye 4 times daily.
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Chống chỉ định
Angle closure glaucoma.
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Thận trọng
Glaucoma, hypertension, CV abnormalities, DM, hyperthyroidism, infection, or injury. Pregnancy and lactation. Avoid in infants and young children <6 yr. Rebound congestion may occur with prolonged use or overuse. Medical advice should be sought if there is ocular pain, vision changes, worsening of redness or irritation of the eye or symptoms lasts > 72 hr. Remove contact lens before use.
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Tác dụng không mong muốn
Blurring of vision, mild stinging and/or irritation, mydriasis and increased or decreased intraocular pressure. When used in high doses in elderly, naphazoline may liberate pigment granules from the iris.
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Tương tác
Increased pressor effects with maprotiline or TCA. Possibility of severe hypertensive reaction with MAOI.
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Tác dụng
Description:
Mechanism of Action: Naphazoline, an imidazoline derivative sympathomimetic with α-adrenergic activity, produces vasoconstriction. When applied topically to mucous membranes, it reduces swelling and congestion. It is often used in combination with antazoline, an ethylenediamine derivative antihistamine, in ophthalmic preparations. Antazoline may be used as the hydrochloride, phosphate, sulfate or mesilate salts in ophthalmic preprations, usually in a concentration of 0.5%. Onset: Local vasoconstriction: within 10 minutes Duration: Local vasoconstriction: 2-6 hr |
Bảo quản
Store at 20-25°C (68-77°F). Protect from light.
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Phân loại MIMS
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